Laboratory
of
Sphingolipid Biology
About Us
Finding Inspiration in Every Turn !
Postdoctoral Fellows
Dr. Trishna Pani
Project Research Scientist-I
M.Sc. Biotechnology, Vellore Institute of Technology
I am interested in deciphering the transcriptional and post-transcriptional alterations in sphingolipid and ganglioside genes during tumor progression. I am focused on understanding the molecular mechanisms orchestrating these alterations and their role in tumor progression.
Dr. Nafees Ansari
Project Research Scientist-I
M.Sc. Microbiology, Central University of Rajasthan
I am interested in building metabolic-signalling-gene regulatory circuits connecting
sphingolipid and ganglioside pathways with cancer progression. I am also interested
to see alterations in chromatin accessibility in context of metabolic signalling during
breast cancer progression.
Dr. Amit Chaudhary
Project Research Scientist-I
PhD, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry
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Ali Khan
PhD Scholar, Amity University, Haryana
M.Sc. Physics, Thapar Institute of Engineering and Technology, Patiala, Punjab
I work on identifying and validating alterations in lipids, such as sphingolipids, phospholipids, eicosanoids, gangliosides, and metabolites, as diagnostic and therapeutic targets for Cancer and Inflammatory diseases. I aim to identify and validate lipid-based signatures in patient samples for use as potential diagnostic and prognostic biomarkers.
PhD Students
Somesh Kumar Jha
PhD Scholar, Regional Centre for Biotechnology, Faridabad
M.Sc. Biotechnology (Int. PhD.), Regional Centre for Biotechnology, Faridabad
​
I am working on the role of immune and lipid regulations in the tumor
microenvironment. One of the aspect I am working on is to delineate the role of
epigenetic modification mediated proteasomal regulation in different murine tumor
microenvironments. The other aspect I am pursuing, is, to study the role of lipid
dysregulation in murine liver cancer models and designing strategies to mitigate it.
Somdeb Chatterjee
PhD Scholar
M.Tech. Biotechnology, KIIT Bhubaneshwar
​
Computational methods can serve as a valuable tool for modeling metabolism in
humans; allowing us to better understand disease states, identify key reactions and
probe their response to perturbations. My interest is in computational biology, with
work revolving around constraint-based modeling and simulation of various aspects
of sphingolipid metabolism in the context of breast cancer.
Rajeshwari tripathi
PhD Scholar
M.Sc. Zoology, Kumaun University, Nainital
I am working on understanding the regulation of sphingolipids and eicosanoids in
progression of Inflammatory Bowel Diseases (IBD) and identify lipid signatures that
can distinguish between different subtypes of IBD. Iam also interested to see the
transcriptional regulation of lipid pathways in different subtypes of breast cancer.
Sayed Mohamad Safwan
PhD Scholar
M.Sc. Lifescience, NIT Rourkela
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Visiting Students
Shivam
Project-JRF
M.Sc. (Biotechnology), Amity University Gurgaon, 2023
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I delves deeper into the sphingolipid-mediated regulation of mTORC2 pathway in multiple cancer models. He is dissecting the intricate coss-talk between RICTOR, the regulatory subunit of mTORC2, and key sphingolipid species for modulating the tumor microenvironment during tumor progression.
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Dolly Jain
Ph.D-SRF, Regional Centre for Biotechnology, Faridabad
M.Sc. Biomedical Sciences, Dr. BR. Ambedkar Center for Biomedical Research, University of Delhi, 2019
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I am working on exploring the impact of different therapeutic interventions on chemotherapy-mediated tumor regression. Dietary restriction regimens including caloric restriction and fasting have emerged as promising strategies to sensitize cancer cells towards chemotherapy while protecting the normal cells. I am exploring the impact of dietary restriction on chemotherapy-mediated tumor regression, and its impact on the tumor microenvironment. Apart from cancer cell-immune cell interactions, cancer cell-neuron interactions are crucial for tumor progression. I am also developing innovative strategies to alter the tumor microenvironment by targeting the cancer cell-neuron interactions.
Jasleen Kaur
PhD-JRF, National Institute of Immunology, Delhi
M.Sc. Life Sciences, Bose Institute Kolkata, 2021
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Project Fellow
Anjali Lakra
M.Sc. (Biotechnology), Amity University Gurgaon, 2023
Sanjana Jangra
M.Sc. (Biotechnology), Amity University Gurgaon, 2023
Bharti Rose
M.Sc. (Biotechnology), Amity University Gurgaon, 2023
Dr. Trishna Pani
Project Research Scientist-I
M.Sc. Biotechnology, Vellore Institute of Technology, 2014
I am interested in deciphering the transcriptional and post-transcriptional alterations in sphingolipid and ganglioside genes during tumor progression. I am focused on understanding the molecular mechanisms orchestrating these alterations and their role in tumor progression.